In his speech in New York, the US president said now was the time for Israel and Hamas to finalise the terms of a ceasefire and hostage release deal in Gaza.

Mr Biden said the families of those taken hostage were "going through hell" and added: "Innocent civilians in Gaza are also going through hell."

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Speaking about Israel and Hezbollah militants in Lebanon edging closer to an all-out war, Mr Biden said: "Full-scale war is not in anyone's interest.

"A diplomatic solution is still possible. In fact, it remains the only path to lasting security."

Mr Biden also condemned Israeli settler violence against Palestinian civilians in the West Bank and said progress towards peace in the Middle East would put the world in a stronger position to respond to "the ongoing threat posed by Iran".

"Together we must deny oxygen to its terrorist proxies," he said - referring to Iran-backed groups Hamas, Hezbollah and Houthi militants in Yemen - "and ensure that Iran will never, ever obtain a nuclear weapon."

He had a more hopeful outlook for the Middle East when he addressed the UN a year ago, when he spoke of a "sustainable, integrated Middle East" coming into view.

During his speech, Mr Biden also praised the support his Western allies have given to Ukraine since Russia invaded in February 2022.

"The good news is Putin's war has failed in its core aim. He set out to destroy Ukraine, but Ukraine is still free," he said.

He called for world leaders to continue their support for Ukraine, adding: "We cannot grow weary. We cannot look away, and we will not let up on our support for Ukraine, not until Ukraine wins with a just, durable peace."

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'Some things are more important than staying in power'

With four months left in office, the speech was one of Mr Biden's last high-profile opportunities as president to put forward the case for American support for Ukraine, which could be placed in doubt if former president Donald Trump defeats vice president Kamala Harris.

Meanwhile, Ukrainian President Volodymyr Zelenskyy is still trying to galvanise Mr Biden into loosening restrictions on the use of Western-supplied long-range missiles, so Ukrainian forces can use them to hit targets in Russia.

Mr Biden will hear from Mr Zelenskyy about a new Ukrainian peace plan when they meet in Washington this Thursday.

During the course of the war, Mr Biden has initially resisted Ukrainian requests for certain military assets, such as M1 Abrams tanks and F-16 fighter jets, before relenting and agreeing to their use.

Mr Biden concluded his final speech to the UN General Assembly as US president with a message to world leaders: "My fellow leaders, let us never forget, some things are more important than staying in power. It's your people."